The advent of newer, brighter, and more coherent X-ray sources, such as X-ray free-electron lasers (XFELs), represents a tremendous growth in the potential to apply coherent X-rays to determine the structure of materials from the micron scale down to the angstrom scale.

We present a framework for Start-to-End (S2E) simulations of a coherent X-ray experiment, including source parameters, propagation of the coherent X-rays though optical elements, interaction of the photons with matter, and their subsequent detection and analysis. The framework documentation, executable and data are publicly available on

The framework also developed into a simulation package, called SIMEX, in the context of the EU-funded project EUCALL. Please contact Carsten Fortmann-Grote for details. SIMEX is available at

C. H. Yoon SLAC National Accelerator Laboratory, Menlo Park, California, USA
M. Yurkov DESY, Hamburg, Germany
E. Schneidmiller DESY, Hamburg, Germany
L. Samoylova European XFEL, Hamburg, Germany
A. Buzmakov A. V. Shubnikov Institute of Crystallography, Moscow, Russia
Z. Jurek CFEL/DESY and the Hamburg Centre for Ultrafast Imaging, Hamburg, Germany
B. Ziaja-Motyka CFEL/DESY and the Hamburg Centre for Ultrafast Imaging, Hamburg, Germany; Institute of Nuclear Physics, Polish Academy of Sciences, Kraków, Poland
R. Santra CFEL/DESY, Hamburg, Germany
T. Tschentscher European XFEL, Hamburg, Germany
N. D. Loh Centre for BioImaging Sciences and Department of Biological Sciences, National University of Singapore, Singapore
A. P. Mancuso European XFEL, Hamburg, Germany