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Contact details

Mancuso, Adrian

Dr. Adrian Mancuso

WP-84 (Scientific Instrument SPB/SFX)
Group Leader, Leading Scientist

+49 (0)40 8998-2512
+49 (0)40 8998-1905
Mailing address
European XFEL GmbH
Holzkoppel 4
22869 Schenefeld


  • Ph.D. Physics, University of Melbourne, Australia (2006)

Employment history

  • Postdoctoral research associate, University of California, Los Angeles (UCLA), USA (2006 – Oct. 2007)
  • Postdoctoral research associate, DESY, Hamburg, Germany (Nov 2007 – 2011)
  • Leading scientist and group leader at European XFEL (since 2011)

Research interests

  • Nanoscale sample imaging using bright, coherent X-ray beams
  • Characterization of wavefront properties of coherent X-ray beams
  • The limits of imaging weakly scattering samples, including biological samples
  • Complete modeling of photon science experiments from start-to-end
  • Instrumentation design for Coherent X-ray Diffractive Imaging (CXDI) experiments

Selected publications

  • C. H. Yoon, et al, A comprehensive simulation framework for imaging single particles and biomolecules at the European X-ray Free-Electron Laser. Scientific Reports, 1–11. (2016)
  • A. P. Mancuso, et al, Technical Design Report: Scientific Instrument Single Particles, Clusters, and Biomolecules (SPB),, (2013)
  • A. Aquila, et al, Fluence thresholds for grazing incidence hard x-ray mirrors. Applied Physics Letters, 106(24), 241905–6. (2015)
  • M. Altarelli & A. P. Mancuso, Structural biology at the European X-ray free-electron laser facility, Phil. Trans. R. Soc. B 369 no. 1647 20130311, (2014).
  • A. P. Mancuso et al., Internal structure of an intact Convallaria majalis pollen grain observed with X-ray Fresnel coherent diffractive imaging, Opt Express 20, 26778–26785 (2012).
  • A. P. Mancuso et al., Coherent-Pulse 2D Crystallography Using a Free-Electron Laser X-Ray Source, Phys. Rev. Lett. 102, 035502 (2009).